Liv 52 is a herbal preparation which is supposed to have protective effects on the liver. It is often prescribed in liver diseases. Liv 52 DS is the "Double Strength" preparation and presumably only half the dose is required to produce the same effect.
Most acute liver diseases like viral hepatitis are self limited and the patient recovers regardless, or perhaps despite the treatment. This phenomenon probably explains the success of many remedies for liver disease.
The website of the Himalaya Drug Company which manufactures the product sites several "Scientific Studies". Many of them were published in their own in-house publications and it is doubtful if they went through a rigorous peer review process. In any case the conflict of interest is obvious. Some, however, have been published in indexed journals and I had a look at two of the most impressive ones:
- Efficacy of an indigenous compound preparation Liv.52 in acute viral hepatitis – A double-blind study
Sama, S.K. Krishnamurthy, L. Ramachandran, K. and Krishnan Lal, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, Indian Journal of Medical Research (1976): 5, 738.
They excluded sick patients to begin with: "Children below ten and adults above forty were excluded from the trial. Patients in whom there was a rapid deterioration of liver functions, or signs of precoma and/or bleeding tendencies were dropped from the trial and regarded as failures."
Naturally all the patients recovered because they dropped from the study any patient who deteriorated. They report that the bilirubin dropped faster in the patients on Liv 52 but "the total recovery, as evidenced by the normalisation of biochemical parameters especially pyruvic transaminase took more or less the same time in the two sets of patients."
In summary, it made no difference to the outcome.
2. Eur J Clin Pharmacol. 1991;40(2):189-91.
Effect of Liv.52, a herbal preparation, on absorption and metabolism of ethanol in humans.
Chauhan BL . Kulkarni RD .
Source
R and D Centre, Himalaya Drug Co. Bombay, India.
Abstract
In 8 social drinkers, the effect of a single dose of Liv.52 or placebo on ethanol absorption has been studied after ingestion of 30 ml whisky in 5 min. The t1/2 absorption with Liv.52 was 3.62 min, significantly less than after placebo, 6.29 min. The peak concentration after Liv.52 (49.9 mg.100 ml-1) was significantly higher than with placebo (40.5 mg.100 ml-1). Whisky 120 ml consumed by regular alcohol users in 1 h, before and following 15 days of Liv.52 treatment produced significantly higher ethanol levels at 2, 3 and 4 h and significantly lower acetaldehyde levels at 3 and 4 h after Liv.52 treatment. Liv.52 enhanced the rate of absorption of ethanol and rapidly reduced acetaldehyde levels, which may explain its hepatoprotective effect on ethanol-induced liver damage.
PMID: 2065700 [PubMed - indexed for MEDLINE]
Note here that this paper is from the Company R&D center. There is an obvious conflict of interest. We cannot expect them to have done an unbiased study. They have not mentioned the P values for the statistical analysis but the chances of demonstrating a significant difference using "8 social drinkers" seem negligible.
In summary, If you are a heavy drinker, you are heading for liver failure in a few years. You may need a liver transplant some day (if you can stop drinking at that point and demonstrate 6 months abstinence) and Liv 52 is not going to protect you, whether single strength or double strength.
In my opinion it is criminal that the company has advertised in a manner that has given you the impression that their product will protect your liver from the effects of alcohol.
125k Views · 133 Upvotes · Not for Reproduction · Answer requested by Anuj Goel
Liv 52- Ayurvedic Liver Supplement
Liv.52 is an exceptional herbal medication from India that is highly suggested and licensed by more than 45 nations and favorably prescribed by doctors worldwide. It is made by the Himalaya Herbal Health Care, the World's most esteemed liver formula. It has been proven through clinical trials and studies that Liv.52 is one of the extremely researched and tested drugs making it the Top Sought after Liver supplement worldwide.
Liv.52 provides a detoxifying action in cleaning and guarding the liver by counteracting the effects of poisons and toxins found in water, drugs, food, and air. Moreover, the holistic function of the liver is assured with its effective combination of herbs that contain antioxidant characteristics in keeping the hepatic parenchyma strong and healthy.
Liv.52 has the best and safe properties to efficiently guard the liver against toxins. It has already been established that Liv.52 is beneficial in fighting against diseases of the liver such as pre-cirrhotic and early cirrhotic conditions, radiation or chemotherapy induced liver damage, hepatitis, elevated liver enzymes, alcohol liver disease, fatty liver conditions, and protein energy malnutrition.
Because of its ability to regulate the amount of cholesterol in the body, it has been proven in over 250 clinical researches that Liv.52 is beneficial for people who are going through rehabilitation of the liver with severe alcoholic problems and Anabolic Steroids usage.
How Liv.52 is Beneficial to the Body
- Liv.52 safeguards and protects the liver by detoxifying all types of dangerous substances and toxins found in water, drugs, food, and air. This is beneficial in the maintenance of a well-conditioned liver especially for those who take in alcohol.
- Liv.52 keeps the liver from accumulating fat and decreases lipotropic action for people diagnosed with chronic alcoholism.
- Liv.52 improves regeneration of liver cells and safeguards the hepatic parenchyma by increasing the proper functionality of the liver.
- Liv.52 is beneficial and famous to individuals who utilize anabolic steroids.
- Liv.52 provides protection from hepatic problems caused by alcohol, improves the capability of the liver, and normalizes the number of hepatic enzymes by quickly removing the dangerous intermediate substance of alcohol metabolism called acetaldehyde.
- Liv.52 is taken to treat hepatitis and cirrhosis, as well as improve the rejuvenation, cleansing, protection, and detoxification of the liver.
- Liv.52 hinders the worsening of pre-cirrhotic diseases and inhibits severe impairment of the liver.
For people who are very mindful for the condition of their liver, Liv.52 may be taken every day as a supplement to increase weight, enrich proper appetite, and enhance the process of absorption and digestion of the body.
In infective hepatitis, Liv.52 promotes early recuperation of liver functions and quickens physical recovery. Liv.52 also keeps cytochrome P-450, prevents hepatotoxic adverse effects for those taking medications, and maintains the normal activity of the cell membrane with its antiperoxidative property.
Liv.52 is healthier to use than milk thistle.
Liv 52- Ingredients
Himsra (Capparis spinosa)
A prostrate shrub or climber armed with divaricate, light yellow thorns. The root bark contains stachydrine, rutic acid and a volatile Nicola Fornasari // SUBSTANCE.IT // home // is bitter, aperient, diuretic and expectorant.
Arjuna (Terminalia arjuna)
Terminalia arjuna is an Ayurvedic cardioprotective botanical medicinal plant being used in Ayurveda since 2500 B.C, widely used by Ayurvedic physicians for its curative properties in organic/functional heart problems including angina. Read More..
Common chicory (Cichorium intybus) also known as blue sailors, is a bushy perennial herb with blue, lavender, or white flowers. Chicory is widely seen in Europe, North America and Australia.
Read More.
The Black nightshade is a fairly common plant a member of the Solanaceae family, found in many wooded areas, as well as disturbed habitats. It rarely grows more than a foot or so in height and is much branched, generally making a bushy-looking mass.
Read More.
Negro Coffee has been traditionally used to promote normal bowel movements. It is a cousin species of Senna, a known and stronger purgative. Despite its name (which comes from its occasional use as a coffee substitute), Negro Coffee is absolutely.
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Mandur bhasma an ayurvedic preparation of iron is used in traditional medicine against hepatitis. In the present study the hepatoprotective property of this drug was tested in albino rats during CCl4 induced hepatic injury.
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Different species of Achillea have been used medicinally from an early date. Dioscorides mentions it as a plant which was used as an astringent and emmenagogue. the origin for the generic name for these plants is by Achilles.
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Tamarix gallica Tamarix gallica is a gregarious bushy shrub that grows on saline or waterlogged soils or a small tree with pendulous branches when grown on better soils. A deciduous shrub growing to 4m by 6m at a medium rate.
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Liv 52- How It works
Liv-52 restores or improves the functional efficiency of the liver by protecting the hepatic parenchyma and promoting hepatocellular regeneration.
Liv-52 regulates levels of liver enzymes and optimizes liver function by rapid elimination of acetaldehyde, the toxic intermediate metabolite of alcohol metabolism, and ensures protection from alcohol-induced hepatic damage
Liv-52 neutralizes all kind of toxins and poisons from food, water, air and medications, the detoxification process cleans and protect the liver. Alcohol users in particular will find Liv-52 helpful in maintaining a healthier liver
The antiperoxidative activity of Liv.52 prevents the loss of functional integrity of the cell membrane, maintains cytochrome P-450, hastens the recovery period and ensures early restoration of hepatic functions in infective hepatitis. (Liv.52 helps those in medication to protect against damaging hepatotoxic side effects.)
Liv.52 diminishes the lipotropic activity in chronic alcoholism, and prevents fatty infiltration of the liver.
In pre-cirrhotic conditions, Liv.52 arrests the progress of the disease and prevents further liver damage.
Liv 52 is best for a regular health conscious individual for liver support. As a daily health supplement, Liv.52 improves appetite, the digestion and assimilation processes, and promotes weight gain.
Liv 52 is very popular among anabolic steroid users.
Liv 52 is better than milk thistle
Liv 52 is used for Liver protection liver detoxification, cirrhosis, hepatitis, liver cleansing and liver rejuvenation.
Have gOOd health….
17.6k Views · 7 Upvotes · Not for Reproduction · Answer requested by Dinesh Varma
No matter what medicine you take it won't nullify the effect of alcohol ,in your case you want to continue taking alcohol and just want to take a medicine on the side which you think will protect your liver from damage .
No boss it's not gonna help
You have to give up drinking for that to work
*Firstly get a L.F.T ( LIVER FUNCTION TEST ) done visit a medical practitioner he'll then tell you as to how much damage you have done to your liver .
These aren't magic pills they are just for proper functioning of your liver
To detox your liver you can do the following :-
#1 Drink Raw Vegetable Juice such as carrot
#2 Take a potassium rich food such as. bananas. sweet potatoes, spinach. beet green (leaves of beet root
#3 Eat Real Liver or Take Liver Tablets
#4 Milk Thistle is considered the “king” of detoxifying herbs, making it ideal for a liver cleanse. Milk thistle helps to eliminate the buildup of heavy metals, prescription medications, environmental pollutants and alcohol in the liver.
Hope my answer helped you
Please see a doctor
4.8k Views · 1 Upvote · Not for Reproduction · Answer requested by Parijat Jha